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Apoorva Srinivasan

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diffusion models for protein generation Introduction Proteins are nature's versatile nanomachines— they have evolved to perform virtually...
30th Dec 2024
81

diffusion models for protein generation

from Apoorva Srinivasan [alt+shift+b] in science

30th Dec 2024
Introduction Proteins are nature's versatile nanomachines— they have evolved to perform virtually every important task in living systems. While nature has produced an incredible range of protein functions, these represent only a tiny fraction of what's possible in the protein...
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a review on protein language models Protein “language” is a lot like human language. Given the similarities, researchers have been...
12th May 2024
45

a review on protein language models

from Apoorva Srinivasan [alt+shift+b] in science

12th May 2024
Protein “language” is a lot like human language. Given the similarities, researchers have been building and training language models on protein sequence data, replicating the success seen in other domains, with profound implications. In this post, I will explore how transformer...
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an experiment in navigating the knowledge frontier beyond search Lately, I've been experimenting with interfaces for large language models (LLMs) in my free time....
21st Nov 2023
35

an experiment in navigating the knowledge frontier beyond search

from Apoorva Srinivasan [alt+shift+b] in science

21st Nov 2023
Lately, I've been experimenting with interfaces for large language models (LLMs) in my free time. The fruit of this labor is something I'm calling "curie," an exploratory and sense-making tool designed to navigate complex topics. 0:00 ...
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what's happened since the human genome project When the human genome project was deemed “complete” in 2003, it was met with incredible fanfare. The...
17th May 2022
33

what's happened since the human genome project

from Apoorva Srinivasan [alt+shift+b] in science

17th May 2022
When the human genome project was deemed “complete” in 2003, it was met with incredible fanfare. The entire project leading up to that moment had all the drama to keep its audience enthralled. Fierce rivalry between a public and private institution, multiple countries involved,...
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niceR code with functional programming At the end of this blog post, you will be able to: Describe functional programming concepts Write...
15th Oct 2020
34

niceR code with functional programming

from Apoorva Srinivasan [alt+shift+b] in science

15th Oct 2020
At the end of this blog post, you will be able to: Describe functional programming concepts Write functional programming code using purrr package in R If you are anything like me, you probably focused primarily on learning statistics, machine learning and programming on a...
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getting started with bayesian inference In my previous post, we spoke about hypothesis testing from a frequentist perspective. This is the...
27th Jun 2020
23

getting started with bayesian inference

from Apoorva Srinivasan [alt+shift+b] in science

27th Jun 2020
In my previous post, we spoke about hypothesis testing from a frequentist perspective. This is the method that is commonly taught in STAT101 classes. But for many decades, some statisticians have argued for another approach to conduct statistical analysis based on bayes...
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on edward jenner and creativity One common question that’s on everyone’s minds as we fiercely scrub our hands, pool our resources,...
20th May 2020
25

on edward jenner and creativity

from Apoorva Srinivasan [alt+shift+b] in science

20th May 2020
One common question that’s on everyone’s minds as we fiercely scrub our hands, pool our resources, conserve our consumption, stock up (but not hoard), invent calculus or write King Lear is: when will this end? Nobody knows what the answer to that question is but we
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