Andreessen Horowitz
A Personal Update
I was well into my career when I discovered the magical world of technology start-ups. This anecdote...
2 weeks ago
I was well into my career when I discovered the magical world of technology start-ups. This anecdote from Adam Lashinsky’s excellent book Inside Apple summarizes the point quite well:
I have been working in this tech start-up space for almost …
The post A Personal Update...
Andreessen Horowitz
How to build in web3: New talks from Crypto Startup School ’23
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The post How to build in web3: New talks from Crypto Startup School ’23 appeared first on...
a month ago
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Andreessen Horowitz
Why AI Will Save the World
The era of Artificial Intelligence is here, and boy are people freaking out.
Fortunately, I am here...
8 hours ago
The era of Artificial Intelligence is here, and boy are people freaking out.
Fortunately, I am here to bring the good news: AI will not destroy the world, and in fact may save it.
First, a short description of what …
The post Why AI Will Save the World appeared first on...
Andreessen Horowitz
Channel Partnerships in Healthcare: A Founder’s Playbook
Over the last decade, many digital health companies have struggled to achieve escape velocity, not...
a month ago
Over the last decade, many digital health companies have struggled to achieve escape velocity, not because their products and services weren’t transformative, but because they failed to find a sustainable path for distribution.
The good news is that resourceful …
The post Channel...
Andreessen Horowitz
Level Up: Welcoming our New Cultural Leadership Fund Nonprofit Partners
Over the last 5 years, the work of the Cultural Leadership Fund (CLF) has been growing and evolving...
3 weeks ago
Over the last 5 years, the work of the Cultural Leadership Fund (CLF) has been growing and evolving to increase access to career paths and leadership roles in technology as an important gateway to wealth generation for the Black community. …
The post Level Up: Welcoming our New...
Andreessen Horowitz
Field Notes: Digital Branding with Susan Plagemann
This is Field Notes, a video podcast series by a16z that explores the business models and behaviors...
a month ago
This is Field Notes, a video podcast series by a16z that explores the business models and behaviors that are changing consumer technology.
In this episode, host Connie Chan talks to Susan Plagemann, the president of WME Fashion and a …
The post Field Notes: Digital Branding with...
Andreessen Horowitz
How the U.S. Can Rewire the Pentagon for a New Era
We are in the early stages of a generational defense cycle that requires unconventional thinking and...
a month ago
We are in the early stages of a generational defense cycle that requires unconventional thinking and tools. The invasion of Ukraine highlights this evolution: comparatively low-cost weapons, from drones to precision artillery, are leveraging cutting-edge networks, like SpaceX’s...
Andreessen Horowitz
Generative AI is Coming for Insurance (May 2023 Fintech Newsletter)
TABLE OF CONTENTS
Generative AI is Coming for Insurance
Because underwriting, selling, and...
a week ago
TABLE OF CONTENTS
Generative AI is Coming for Insurance
Because underwriting, selling, and servicing rely so heavily on humans processing large quantities of written or verbal communication, existing tools have struggled to properly automate these services and materially...
Andreessen Horowitz
The 16 Commandments of Raising Equity in a Challenging Market
Between inflation, rising interest rates, geopolitical tensions, and growing recession concerns,...
a month ago
Between inflation, rising interest rates, geopolitical tensions, and growing recession concerns, 2022 was a year of reckoning for both public and private markets. Since the beginning of 2022, the tech-heavy Nasdaq Composite has declined 23% (versus the S&P 500’s 14% …
The post...
Andreessen Horowitz
The Rise of Composable the CDP
In our popular post on emerging data infrastructure, we highlighted technologies that have led to a...
2 weeks ago
In our popular post on emerging data infrastructure, we highlighted technologies that have led to a new wave of data-stack investments. These stacks represent the culmination of a number of trends in the industry, including the migration from on-prem …
The post The Rise of...
Andreessen Horowitz
The New Industrial Revolution: Bio x AI
Editor’s note: This piece was originally published in October 2021. We continue to be bullish on the...
2 weeks ago
Editor’s note: This piece was originally published in October 2021. We continue to be bullish on the power of AI to transform bio + health—especially as AI continues to drive the very industrial bio complex Vijay discusses below.
We’ve now …
The post The New Industrial...
Andreessen Horowitz
Hiring in web3: 4 principles for finding talent in volatile times
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a month ago
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Andreessen Horowitz
Our Cities Have an API Problem. Startups Can Fix It.
“Cities are technological artifacts,” Kevin Kelly once wrote, “the largest technology we make.” What...
8 months ago
“Cities are technological artifacts,” Kevin Kelly once wrote, “the largest technology we make.” What if we looked at America’s cities not metaphorically as tech, but literally as a technological system? Rather than fighting about politics, we’d ask our cities the mundane...
Andreessen Horowitz
Bat Out of Hell: Identifying Your Durable Advantage in Fintech
Imagine you are the founder of a fintech company that’s identified a massive broken market. As I’ve...
2 weeks ago
Imagine you are the founder of a fintech company that’s identified a massive broken market. As I’ve previously written about, to build your product and identify potential market opportunities, you’ve likely begun buying growth through paid acquisition channels. That …
The post...
Andreessen Horowitz
Financial Services Will Embrace Generative AI Faster Than You Think
Artificial intelligence and machine learning have been used in the financial services industry for...
a month ago
Artificial intelligence and machine learning have been used in the financial services industry for more than a decade, enabling enhancements that range from better underwriting to improved foundational fraud scores. Generative AI via large language models (LLMs) represents a...
Andreessen Horowitz
Building Cicada: Private on-chain voting using time-lock puzzles
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The post Building Cicada: Private on-chain voting using time-lock puzzles appeared first on...
a week ago
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Andreessen Horowitz
5 Founders on the Future of Data
It’s well understood that artificial intelligence is advancing like mad right now. What’s less...
3 weeks ago
It’s well understood that artificial intelligence is advancing like mad right now. What’s less appreciated is the role that data and infrastructure continue to play in these advances — whether that’s adding new data sources to train better models, building …
The post 5 Founders...
Andreessen Horowitz
Using Generative AI to Unlock Probabilistic Products
One remarkable thing about the invention of generative AI is that it’s one of the first examples of...
2 weeks ago
One remarkable thing about the invention of generative AI is that it’s one of the first examples of a probabilistic computer that produces outputs that are varied and non-deterministic. Some, who expect these systems to behave like traditional systems, have …
The post Using...
Andreessen Horowitz
Both Sides of the Partnership: Executing Lyft’s “Impossible” Ask
If business partnerships are a high-stakes form of matchmaking, then the strategic partnership...
a month ago
If business partnerships are a high-stakes form of matchmaking, then the strategic partnership between Lyft and the automotive services giant Holman was something of an odd-couple proposition at the start. When first broached five years ago, the companies’ working styles …
The...
Andreessen Horowitz
Embracing the Future: How Chatbots Can Become Great Companions
“Being deeply loved by someone gives you strength, while loving someone deeply gives you courage....
a month ago
“Being deeply loved by someone gives you strength, while loving someone deeply gives you courage. But being understood by someone is everything.” – Lao Tzu
Psychologist Abraham Maslow famously posited that human behavior can be classified into a hierarchy of …
The post Embracing...
Andreessen Horowitz
How To Democratize Healthcare: AI Gives Everyone The Very Best Doctor
Editor’s note: This piece was originally published in May 2018.
The greatest problem of health care...
5 days ago
Editor’s note: This piece was originally published in May 2018.
The greatest problem of health care in United States–the world leader in health inequality–isn’t actually about the quality of care. The greatest problem we have is access to …
The post How To Democratize...
Andreessen Horowitz
Navigating the High Cost of AI Compute
Source: Midjourney
The generative AI boom is compute-bound. It has the unique property that adding...
a month ago
Source: Midjourney
The generative AI boom is compute-bound. It has the unique property that adding more compute directly results in a better product. Usually, R&D investment is more directly tied to how valuable a product was, and that relationship is …
The post Navigating the...
Andreessen Horowitz
It’s Time to Build For America: Announcing Our $500M+ Commitment to Companies Building in American...
We formalized our American Dynamism practice a little more than a year ago to galvanize support for...
4 weeks ago
We formalized our American Dynamism practice a little more than a year ago to galvanize support for solving our country’s most vexing challenges with an entrepreneurial and technology-first approach. We’ve been blown away at how this movement has captured the …
The post It’s Time...
Andreessen Horowitz
Beyond Payments for High-Risk Industries
Today, most merchants looking to sell a product or service online can quickly get their payment...
a month ago
Today, most merchants looking to sell a product or service online can quickly get their payment system live with the help of a modern checkout platform. If the merchant works in a “high-risk” industry like games, sports betting, telehealth, …
The post Beyond Payments for...
Andreessen Horowitz
Investing in Pinecone
With the inflection of large language models (LLMs), we’re witnessing a paradigm shift in software...
a month ago
With the inflection of large language models (LLMs), we’re witnessing a paradigm shift in software development and the computing industry as a whole. AI is happening and a new stack is forming before our eyes. It’s like the Internet all …
The post Investing in Pinecone appeared...
Andreessen Horowitz
Investing in Orbital Therapeutics
“The fact that proteins are not synthesized directly on genes demands the existence of an...
a month ago
“The fact that proteins are not synthesized directly on genes demands the existence of an intermediate information carrier…which receives genetic information from the gene in the form of an unstable intermediate…a special type of RNA molecule, or ‘messenger RNA’.”
– …
The post...
Andreessen Horowitz
Investing in Radiant
Most people don’t know that nuclear energy — a clean, carbon-free energy source — accounts for 20%...
a month ago
Most people don’t know that nuclear energy — a clean, carbon-free energy source — accounts for 20% of electricity in the United States and over half of its carbon-free electricity. However, while large nuclear reactors are often (erroneously) villainized — …
The post Investing in...
Andreessen Horowitz
Enterprise Startups: Advice on Hiring, Firing, Scaling, and Selling
A16z recently brought together a group of early-stage CEOs to talk shop and learn from their peers...
3 weeks ago
A16z recently brought together a group of early-stage CEOs to talk shop and learn from their peers who have successfully navigated the journey from scrappy startup into large growth-stage or even public companies. The event featured a series of interviews …
The post Enterprise...
Andreessen Horowitz
Hey Tech, It’s Time To Build. In Healthcare.
In the past few months, the founders of Instacart, Spotify, and Coinbase have all started new...
a month ago
In the past few months, the founders of Instacart, Spotify, and Coinbase have all started new healthcare companies. This may seem odd to some–why are these seasoned tech founders jumping into tech-driven healthcare?
In 2013, Marc Andreessen observed that the …
The post Hey Tech,...
Andreessen Horowitz
AI Canon
Source: Midjourney
Research in artificial intelligence is increasing at an exponential rate. It’s...
a week ago
Source: Midjourney
Research in artificial intelligence is increasing at an exponential rate. It’s difficult for AI experts to keep up with everything new being published, and even harder for beginners to know where to start.
So, in this post, we’re …
The post AI Canon appeared...
Andreessen Horowitz
Investing in Hippocratic AI
“Solving consumer engagement is worth $1 trillion to our organization,” said a health plan executive...
3 weeks ago
“Solving consumer engagement is worth $1 trillion to our organization,” said a health plan executive to me one day. He was obviously being a bit sensationalist with the magnitude of the number, but it’s been a common thread in strategic …
The post Investing in Hippocratic AI...
Andreessen Horowitz
Field Notes: Resale Social Marketplaces with Tracy Sun
This is Field Notes, a new video podcast series by a16z that explores the business models and...
a month ago
This is Field Notes, a new video podcast series by a16z that explores the business models and behaviors that are changing consumer technology.
In this episode, host Connie Chan talks to Tracy Sun, the cofounder and SVP of …
The post Field Notes: Resale Social Marketplaces with...
Andreessen Horowitz
Grow or Die: A Framework for Turning Your Company Around Fast
This post originally ran here. Most great teams would agree, there’s nothing more powerful for...
9 months ago
This post originally ran here. Most great teams would agree, there’s nothing more powerful for executing on big ambitions than a clearly defined and well-communicated goal. But sometimes the stakes are much higher than usual. In these instances, a goal requires even more focus,...
Andreessen Horowitz
Did We Overeat on Software?
It’s been a little over a decade since Marc Andreesen famously declared that software was eating the...
8 months ago
It’s been a little over a decade since Marc Andreesen famously declared that software was eating the world. He was right. Now, we’re in a new phase: There is powerful software everywhere we look, and we’ve been consuming it without much regard for the long-term effects. So much...
Andreessen Horowitz
Field Notes: Investing in Global Tech with Chris Schroeder
This is Field Notes, a new video podcast series by a16z that explores the business models and...
a month ago
This is Field Notes, a new video podcast series by a16z that explores the business models and behaviors that are changing consumer technology. Subscribe to the a16z channel on YouTube so you don’t miss an episode.
In this episode, …
The post Field Notes: Investing in Global...
Andreessen Horowitz
Full-Stack Startups in American Dynamism
The full-stack startup, as previously written about by our partner Chris Dixon, is an approach taken...
a week ago
The full-stack startup, as previously written about by our partner Chris Dixon, is an approach taken by some startups to bypass incumbents by building a complete, end-to-end product or service. This approach is in contrast to the traditional approach, …
The post Full-Stack...
Andreessen Horowitz
Why Applying Machine Learning to Biology is Hard – But Worth It
Jimmy Lin is CSO of Freenome, which is developing blood-based tests for early cancer detection,...
8 months ago
Jimmy Lin is CSO of Freenome, which is developing blood-based tests for early cancer detection, starting with colon cancer. He is a pioneer in developing computational approaches to extract insights from large-scale genomic data, having spearheaded the computational analyses of...
Andreessen Horowitz
Jason Fried on Why He Doesn’t Do Planning or Politics at Work
Compared with many startups, 37signals cofounder Jason Fried’s views around workplace culture,...
9 months ago
Compared with many startups, 37signals cofounder Jason Fried’s views around workplace culture, structure, and strategy could be considered subversive. He’d call them “honest,” a word he uses often when describing his leadership style. The outspoken maker of Basecamp and HEY has...
Andreessen Horowitz
Thinking Through CC0 and IP for NFT Communities
Welcome to Web3 Water Cooler, a moderated Slack chat about a trending topic in crypto. This week’s...
9 months ago
Welcome to Web3 Water Cooler, a moderated Slack chat about a trending topic in crypto. This week’s participants are Orca Protocol’s Chase Chapman, Austin Hurwitz of Venice Music, and IP lawyer Nuzayra Haque-Shah. NFTs are a web3 innovation, but the intellectual property...
Andreessen Horowitz
How to Build a GPT-3 for Science
Want to create an image of velociraptors working on a skyscraper, in the style of “Lunch Atop A...
9 months ago
Want to create an image of velociraptors working on a skyscraper, in the style of “Lunch Atop A Skyscraper” of 1932? Use DALL-E. Want to create an imaginary standup comedy show by Peter Thiel, Elon Musk, and Larry Page? Use GPT-3. Want to deeply understand COVID-19 research and...
Andreessen Horowitz
Aligning Founder Superpowers with Product Cycles
Watching the generative AI space shape up over the past several months has reaffirmed my belief...
2 weeks ago
Watching the generative AI space shape up over the past several months has reaffirmed my belief that, as product cycles mature, different types of builders have leverage at different moments in the cycle. And, at this early stage in generative …
The post Aligning Founder...
Andreessen Horowitz
Research Twice, Build Once: How to Know Your Users as You Grow
Far too many products still fail because there’s simply no demand for them. How does that happen?...
9 months ago
Far too many products still fail because there’s simply no demand for them. How does that happen? Or, how do so many startups launch entire businesses without realizing users didn’t need their products? By overlooking user research. Every tech company has to build and ship new...
Andreessen Horowitz
What Synthetic Embryos Can and Can’t Do, Now and in the Future
Magdalena Zernicka-Goetz is the Bren Professor of Biology and Biological Engineering at the...
9 months ago
Magdalena Zernicka-Goetz is the Bren Professor of Biology and Biological Engineering at the California Institute of Technology and a Professor of Stem Cell Biology and Development at the University of Cambridge. In this interview, we discuss recent advances in technologies that...
Andreessen Horowitz
Remote Startups Will Win the War for Top Talent
The ease and speed with which you can now buy nearly anything — truly, anything — online is often...
9 months ago
The ease and speed with which you can now buy nearly anything — truly, anything — online is often taken for granted: not just food, but cars, homes, blue-chip art, even a college education. In the past 30 years, we have grown to trust the internet in a way we could never have...
Andreessen Horowitz
The 2022 Effect: A Benchmarking Bulletin
When we released a16z Growth’s Guide to Growth Metrics at the end of last year, one of the biggest...
2 days ago
When we released a16z Growth’s Guide to Growth Metrics at the end of last year, one of the biggest requests we received from founders was more information about how companies in our dataset were affected by 2022 macroeconomic conditions. We’re …
The post The 2022 Effect: A...
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