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Protein “language” is a lot like human language. Given the similarities, researchers have been building and training language models on protein sequence data, replicating the success seen in other domains, with profound implications. In this post, I will explore how transformer models have been applied to protein data
12 months ago

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More from Apoorva Srinivasan

diffusion models for protein generation

Introduction Proteins are nature's versatile nanomachines— they have evolved to perform virtually every important task in living systems. While nature has produced an incredible range of protein functions, these represent only a tiny fraction of what's possible in the protein universe. Evolution has only explored

4 months ago 58 votes
an experiment in navigating the knowledge frontier beyond search

Lately, I've been experimenting with interfaces for large language models (LLMs) in my free time. The fruit of this labor is something I'm calling "curie," an exploratory and sense-making tool designed to navigate complex topics. 0:00 0:34 1× the limitations of

a year ago 18 votes
what's happened since the human genome project

When the human genome project was deemed “complete” in 2003, it was met with incredible fanfare. The entire project leading up to that moment had all the drama to keep its audience enthralled. Fierce rivalry between a public and private institution, multiple countries involved, 3.5 billion dollars

over a year ago 18 votes
niceR code with functional programming

At the end of this blog post, you will be able to: Describe functional programming concepts Write functional programming code using purrr package in R If you are anything like me, you probably focused primarily on learning statistics, machine learning and programming on a smaller scale early on in your

over a year ago 18 votes

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8 hours ago 2 votes
Floating Nuclear Power Plants

This is an intriguing idea, and one that I can see becoming critical over the next few decades, or never manifesting – developing a fleet of floating nuclear power plants. One company, Core Power, is working on this technology and plans to have commercially deployable plants by 2035. Company press releases touting their own technology […] The post Floating Nuclear Power Plants first appeared on NeuroLogica Blog.

19 hours ago 1 votes
The evolution of psychiatry

How to separate order from disorder

16 hours ago 1 votes
The Molecular Bond That Helps Secure Your Memories

How do memories last a lifetime when the molecules that form them turn over within days, weeks or months? An interaction between two proteins points to a molecular basis for memory. The post The Molecular Bond That Helps Secure Your Memories first appeared on Quanta Magazine

2 days ago 1 votes
An 80,000-year history of the tomato

Creating the perfect vegetable

2 days ago 1 votes